利用中美冠科數據庫,快速查找所需模型
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白皮書

中美冠科生物通過協助生物制藥公司解決當今腫瘤學和心血管與代謝疾病中最緊迫的問題為世界藥物研發帶來曙光。

New White Paper: Optimize Target Identification and MOA Studies

How to Use CrownBio’s Integrated Oncology Portfolio for Target Identification and Mechanism of Action Elucidation

Correctly identifying drug targets and elucidating MOA is a critical stage in early drug development. Disease-relevant cell-based platforms are needed, which can quickly and easily transition to linked later stage ex vivo and in vivo models, for efficient go/no go preclinical program decisions.

This White Paper covers how to optimize the main stages of cell line selection, downstream target characterization and expression analyses, and translation of in vitro to in vivo studies.

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  • The importance of cell line selection, using collated databases containing large cell line collections, or bespoke model creation
  • How to select the correct downstream molecular biology assays to assess target expression, drug target inhibition, and tumor growth inhibition
  • How an integrated in vitro, ex vivo, and in vivo oncology portfolio allows go/no go decisions to be made with confidence, using a single, uniquely positioned provider

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